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Many implementations around the world. Some of these implementations have nothing todo with genomes.

Can run from local, cloud, etc
Globus genomics is platform optimized for fast file transfer
Galaxy has flexible and broad method of getting data from many sources

observations
not the most efficient to ask question but very flexible, runs good on large computer systems
tools not very helpful for T3 but the platform is designed well
3 windows: tools, options, history
workflow window very good also has option for analyzing multiple files at once

Galaxy is much easier than learning command line but still requires some training 

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