The (older) iWork software from Apple "allows ChemDraw extraction from older Keynote presentations", per Prof. Coates.

Summary

• 2/6/2018 (current MacOS is 10.13.3, High Sierra)

Q: Will iWork’09 work on OS 10.12.6? (INC000002165000)

A: Yes, per Prof. Geoff Coates:

• Just loaded - seems to work fine!

Details

• Prof. Coates had the need so he just bought a copy of iWork and gave it a shot. And it just worked for him.
  • Interesting to learn of this motivation to use 8+ old software.
• Chemistry IT doesn't have experience with iWork in general and iWork'09 in particular.
  • This page created in case others have this compatibility question.

Other resources

Apple's posted requirements are understandably very dated so we must take their "or later" statement about the OS with a grain of salt:

https://support.apple.com/kb/SP676?locale=en_US&viewlocale=en_US
iWork '09 system requirements

• A Mac with an Intel, PowerPC G5, or PowerPC G4 (500MHz or faster) processor
• 512MB of RAM; 1GB recommended
• Approximately 1.2GB of available disk space
• 32MB of video memory
• Mac OS X v10.4.11 or Mac OS X v10.5.6 or later
• QuickTime 7.5.5 or later
• DVD drive required to install
• Some features may require Internet access; additional fees and terms apply