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Relevant genetic characteristics: Whole genome sequences for 15 strains of S. Heidelberg have been deposited at GenBank as of October, 2013. Genomic characteristics of the sequenced S. Heidelberg include (i) a genome size ranging from 4.73 to 4.98 Mb, (ii) a mol G+C% of 52.1, and (iii) 5,578 to 5,039 predicted genes. Many of these sequenced strains have been implicated in recent outbreaks (2011 and 2012), in the U.S. Salmonella Heidelberg str. SARA33 is a multidrug resistant strain. This strain was found, in silico, to contain a novel integron cassette; in addition, it was found to carry the following resistance genes: aac(6′)-ly, aadA5, aadB, aa(6′)-33, and aadA1, sul1 and sul2, blaOXA-2 and blaTEM, tetD. Resistance genes in S. Heidelberg have been identified in the chromosome (resistant islands) and in plasmids. Different incompatibility types (A/C, FIB, HI2) have been identified in the Plasmids plasmids that carried resistance genes in S. Heidelberg.

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