...

• For those using Office 2011 on Macs, it was possible to be able to drag and drop from Chemdraw into Word 2011 and drag and drop the image back into Chemdraw for editing. This is no longer the case for Office 2016.
• Dragging and dropping from ChemDraw 15.1 to Word 2016 will paste an image into the Word document but the image will NOT be editable
• Copying(⌘+C) and Pasting (⌘+V) will only paste text into Word(2016)
• IMPORTANT: Opening an old Office 2011 file in Office 2016 and re-saving it will not affect the images already in the document (you can drag them into Chemdraw for editing). However, anything dragged into Office 2016 will still not be editable.
  • You must instead "Paste as PDF" (via menu or via ⌘+Control+V).
    

Supporting documentation

• Issue came up with MS Office 2016, back in version ChemDraw v13:http://www.cambridgesoft.com/support/DesktopSupport/KnowledgeBase/SystemRequirements/
  
  • http://disq.us/p/z7dtk1
• Still a noted issue with ChemDraw v15:
  
  • http://media.cambridgesoft.com/support/manuals/15_1/ChemOffice%20v15.1%20Release%20Notes.pdf

7 Known Issues, Limitations and Workarounds (as of download date 10/31/2016)

The following list describes the known issues, limitations, and workarounds for ChemOffice 15.1:

• When you copy any object from ChemDraw (Mac) and paste (default) in MS Word 2016, it pastes an MOL text version of that object instead of the original object view.

o Workaround: Use the 'Paste Special >> PDF option in MS Word to get the original object view pasted. This PDF object can be copied back to ChemDraw by maintaining all ChemDraw object properties.